Analysis of U-Net Neural Network Training Parameters for Tomographic Images Segmentation

Keywords: Deep Learning, Biomedical Image Segmentation, Fully Convolutional Networks, U-Net, Computed Tomography

Abstract

Image segmentation is one of the main resources in computer vision. Nowadays, this procedure can be made with high precision using Deep Learning, and this fact is important to applications of several research areas including medical image analysis. Image segmentation is currently applied to find tumors, bone defects and other elements that are crucial to achieve accurate diagnoses. The objective of the present work is to verify the influence of parameters variation on U-Net, a Deep Convolutional Neural Network with Deep Learning for biomedical image segmentation. The dataset was obtained from Kaggle website (www.kaggle.com) and contains 267 volumes of lung computed tomography scans, which are composed of the 2D images and their respective masks (ground truth). The dataset was subdivided in 80% of the volumes for training and 20% for testing. The results were evaluated using the Dice Similarity Coefficient as metric and the value 84% was the mean obtained for the testing set, applying the best parameters considered.

DOI

Downloads

Download data is not yet available.

References

F. Chollet, Deep Learning with Python. Manning Publications; 2017. ISBN 9781617294433.

W. Zhang et al., “Deep convolutional neural networks for multi-modality isointense infant brain image segmentation,” Neuroimage, vol. 108, pp. 214–224, Mar. 2015, doi: 10.1016/j.neuroimage.2014.12.061.

Y. Lecun, E. Bottou, Y. Bengio, and P. Haffner, “Gradient-Based Learning Applied to Document Recognition”, 1998.

O. Oktay et al., “Attention U-Net: Learning Where to Look for the Pancreas,” Apr. 2018, [Online]. Available: http://arxiv.org/abs/1804.03999

D. Shen, G. Wu, and H.-I. Suk, “Deep Learning in Medical Image Analysis,” 2017, doi: 10.1146/annurev-bioeng-071516.

X. Liu, L. Song, S. Liu, and Y. Zhang, “A review of deep-learning-based medical image segmentation methods,” Sustainability (Switzerland), vol. 13, no. 3, pp. 1–29, Feb. 2021, doi: 10.3390/su13031224.

S. Haykin, Neural Networks: A Comprehensive Foundation., Prentice-Hall, 1999.

P. Goyal et al., “Accurate, Large Minibatch SGD: Training ImageNet in 1 Hour,” Jun. 2017, [Online]. Available: http://arxiv.org/abs/1706.02677.

J. Deng, W. Dong, R. Socher, L.-J. Li, K. Li, and L. Fei-Fei, ImageNet: A Large-Scale Hierarchical Image Database. IEEE, 2009.

M. Nishio et al., “Computer-aided diagnosis of lung nodule classification between benign nodule, primary lung cancer, and metastatic lung cancer at different image size using deep convolutional neural network with transfer learning,” PLoS One, vol. 13, no. 7, Jul. 2018, doi: 10.1371/journal.pone.0200721.

A. Ashour, Y. Guo, and Mohamed W., “Medical Image Segmentation.”

I. Goodfellow, A. Courville and Y. Bengio. Deep Learning (Adaptive Computation and Machine Learning Series).

D. Nie, L. Wang, Y. Gao, and D. Sken, “Fully convolutional networks for multi-modality isointense infant brain image segmentation,” in Proceedings - International Symposium on Biomedical Imaging, Jun. 2016, vol. 2016-June, pp. 1342–1345. doi: 10.1109/ISBI.2016.7493515.

O. Ronneberger, P. Fischer, and T. Brox, “U-net: Convolutional networks for biomedical image segmentation,” in Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), 2015, vol. 9351, pp. 234–241. doi: 10.1007/978-3-319-24574-4_28.

I. Kandel and M. Castelli, “The effect of batch size on the generalizability of the convolutional neural networks on a histopathology dataset,” ICT Express, vol. 6, no. 4, pp. 312–315, Dec. 2020, doi: 10.1016/j.icte.2020.04.010.

G. Raskutti, M. J. Wainwright, and B. Yu, “Early Stopping and Non-parametric Regression: An Optimal Data-dependent Stopping Rule,” 2014.

K. Paiva et al., “Performance evaluation of segmentation methods for assessing the lens of the frog Thoropa miliaris from synchrotron-based phase-contrast micro-CT images,” Physica Medica, vol. 94, pp. 43–52, Feb. 2022, doi: 10.1016/j.ejmp.2021.12.013.

M. Moura and A. Meneses, “Evaluation Of Unet Convolutional Neural Network Parameters For Segmentation Of Heart CT Images”. Available in the annals of XXIV National Meeting of Computacional Modeling (ENMC).

A. Saood and I. Hatem, “COVID-19 lung CT image segmentation using deep learning methods: U-Net versus SegNet,” BMC Med Imaging, vol. 21, no. 1, Dec. 2021, doi: 10.1186/s12880-020-00529-5.

V. Thambawita, I. Strümke, S. A. Hicks, P. Halvorsen, S. Parasa, and M. A. Riegler, “Impact of image resolution on deep learning performance in endoscopy image classification: An experimental study using a large dataset of endoscopic images,” Diagnostics, vol. 11, no. 12, Dec. 2021, doi: 10.3390/diagnostics11122183.

C. Shorten and T. M. Khoshgoftaar, “A survey on Image Data Augmentation for Deep Learning,” J Big Data, vol. 6, no. 1, Dec. 2019, doi: 10.1186/s40537-019-0197-0.

A. Dmitrienko, C. Chuang-Stein, R. D’Agostino. “Pharmaceutical Statistics Using SAS”, 2014. In Journal of Chemical Information and Modeling (Vol. 53, Issue 9). SAS Publishing.

M. Neuhauser. “Nonparametric Statistical Tests”, 2011. Chapman and Hall/CRC. https://doi.org/10.1201/b11427.

Published
2023-07-07
How to Cite
[1]
Y. Pereira, D. da Silva, R. Barroso, and A. de Moura Meneses, “Analysis of U-Net Neural Network Training Parameters for Tomographic Images Segmentation”, LAJC, vol. 10, no. 2, pp. 84-95, Jul. 2023.
Section
Research Articles for the Regular Issue